Article
Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.
Diabetes - 1 Feb 2009
Rong Rong, Hanson Robert L, Ortiz Daniel, Wiedrich Christopher, Kobes Sayuko, Knowler William C, Bogardus Clifton, Baier Leslie J
Abstract excerpt
OBJECTIVE: In recent genome-wide association studies, variants in CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, CDKN2B, LOC387761, and FTO were associated with risk for type 2 diabetes in Caucasians. We investigated the association of these single nucleotide polymorphisms (SNPs) and some additional tag SNPs with type 2 diabetes and related quantitative traits in Pima Indians. RESEARCH DESIGN AND METHODS: Forty-seven SNPs...
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