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Article

Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

PloS one - 1 Jan 2015

Mascarenhas Roshan, Pietrzak Maciej, Smith Ryan M, Webb Amy, Wang Danxin, Papp Audrey C, Pinsonneault Julia K, Seweryn Michal, Rempala Grzegorz, Sadee Wolfgang

Abstract excerpt

mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, pointing to polysomal loading as a critical factor. To study regulation and genetic factors of protein translation we measured levels and allelic ratios of mRNAs and...

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Share to Arylamine N-Acetyltransferase
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26331722
DOI: 10.1371/journal.pone.0136798
PMCID: PMC4558023

Genes

ABCB1
NAT1
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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