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Article

The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS

29 Aug 2015

Abstract excerpt

BACKGROUND: In recent years, genome wide association studies have identified many genetic variants that are consistently associated with common complex diseases, but the amount of heritability explained by these risk alleles is still low. Part of the missing heritability may be due to genetic heterogeneity and small sample sizes, but non-optimal study designs in many genome wide association studies may also have...

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PMID: 26319230
DOI: 10.1186/s12881-015-0210-1

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