Article

Mathematical bounds on <i>r</i> <sup>2</sup> and the effect size in case-control genome-wide association studies

2024-12-17

Abstract excerpt

Case-control genome-wide association studies (GWAS) are often used to find associations between genetic variants and diseases. When case-control GWAS are conducted, researchers must make decisions regarding how many cases and how many controls to include in the study. Depending on differing availability and cost of controls and cases, varying case fractions are used in case-control GWAS. Connections between varian...

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Literature Corpus work: 2af8a4f5-1dce-5259-96ca-90d5f9544b60
DOI: 10.1101/2024.12.17.628943

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