Article
[Competing risks of death and Hardy-Weinberg equilibrium in case-control studies of gene-disease association].
Gaceta sanitaria - 1 Jan 2000
Llorca Javier, Prieto-Salceda Dolores, Combarros Onofre, Dierssen-Sotos Trinidad, Berciano José
Abstract excerpt
OBJECTIVE: To study the impact of competing risks on Hardy-Weinberg equilibrium and their consequences in case-control studies of gene-late onset disease association. METHODS: Based on a population born in Hardy-Weinberg equilibrium for a particular gene, the genetic composition when the gene is associated with a lethal early-onset disease and its consequences on a late-onset disease can be deduced. Odds ratios...
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