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Article

Systematic interpretation of comutated genes in large-scale cancer mutation profiles.

Molecular cancer therapeutics - 1 Aug 2010

Gu Yunyan, Yang Da, Zou Jinfeng, Ma Wencai, Wu Ruihong, Zhao Wenyuan, Zhang Yuannv, Xiao Hui, Gong Xue, Zhang Min, Zhu Jing, Guo Zheng

Abstract excerpt

By high-throughput screens of somatic mutations of genes in cancer genomes, hundreds of cancer genes are being rapidly identified, providing us abundant information for systematically deciphering the genetic changes underlying cancer mechanism. However, the functional collaboration of mutated genes is often neglected in current studies. Here, using four genome-wide somatic mutation data sets and pathways defined...

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PMID: 20663929
DOI: 10.1158/1535-7163.MCT-10-0022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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