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Article

Combinatorial patterns of somatic gene mutations in cancer.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2008

Yeang Chen-Hsiang, McCormick Frank, Levine Arnold

Abstract excerpt

Cancer is a complex process in which the abnormalities of many genes appear to be involved. The combinatorial patterns of gene mutations may reveal the functional relations between genes and pathways in tumorigenesis as well as identify targets for treatment. We examined the patterns of somatic mutations of cancers from Catalog of Somatic Mutations in Cancer (COSMIC), a large-scale database curated by the...

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Identifiers

PMID: 18434431
DOI: 10.1096/fj.08-108985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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