Article
Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse.
Oncotarget - 22 Sept 2015
Yu Ke-Da, Wang Xin, Yang Chen, Zeng Xiao-Hua, Shao Zhi-Ming
Abstract excerpt
PURPOSE: Chemokines may play vital roles in breast cancer progression and metastasis. The primary members of chemokine decoy receptors (CDR), DARC and D6, are expressed in breast tumors and lymphatic/hematogenous vessels. CDRs sequestrate the pro-malignant chemokines. We hypothesized that breast...
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