Article
The impact of the stromal cell-derived factor-1-3'A and E-selectin S128R polymorphisms on breast cancer.
Molecular biology reports - 1 Jan 2013
Kontogianni Panagiota, Zambirinis Constantinos P, Theodoropoulos George, Gazouli Maria, Michalopoulos Nikolaos V, Flessas John, Liberi Maria, Zografos George C
Abstract excerpt
Breast cancer is prone to metastasis even in early stage disease. Stromal cell-derived factor-1 (SDF-1) is a chemokine that has been associated with the egress of cancer cells from the primary focus and homing to distant sites, while E-selectin has been implicated in their trans-endothelial migration. This study was performed to evaluate the association between SDF-1-3'A and E-selectin S128R-two polymorphisms...
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