Article
Plasma stromal cell-derived factor-1: host derived marker predictive of distant metastasis in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2008
Hassan Saima, Baccarelli Andrea, Salvucci Ombretta, Basik Mark
Abstract excerpt
PURPOSE: Homing of breast cancer cells to metastatic sites may be regulated by the production of stromal cell-derived factor (SDF)-1 by specific target organs, which attracts CXCR4-expressing breast cancer cells. We investigated the value of SDF-1 as a predictive blood marker of distant metastasis in breast cancer, together with a common polymorphism of SDF-1, SDF-1-3'A. EXPERIMENTAL DESIGN: Plasma samples were...
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