Article
Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Experimental neurology - 1 Nov 2015
Xu Leyan, Ryu Jiwon, Nguyen Judy V, Arena John, Rha Elizabeth, Vranis Pamela, Hitt Devon, Marsh-Armstrong Nicholas, Koliatsos Vassilis E
Abstract excerpt
Chronic traumatic encephalopathy (CTE) is associated with repetitive mild traumatic brain injury (mTBI) in the context of contact and collision sports, but not all exposed individuals develop this condition. In addition, experiments in animal models in several laboratories have shown that non-transgenic mice do not develop tauopathy after exposure to repetitive mTBI schedules. It is thus reasonable to assume that...
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