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Article

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat.

Bone - 1 Dec 2015

Alam Imranul, Koller Daniel L, Cañete Toni, Blázquez Gloria, Mont-Cardona Carme, López-Aumatell Regina, Martínez-Membrives Esther, Díaz-Morán Sira, Tobeña Adolf, Fernández-Teruel Alberto, Stridh Pernilla, Diez Margarita, Olsson Tomas, Johannesson Martina, Baud Amelie, Econs Michael J, Foroud Tatiana

Abstract excerpt

We previously demonstrated that skeletal structure and strength phenotypes vary considerably in heterogeneous stock (HS) rats. These phenotypes were found to be strongly heritable, suggesting that the HS rat model represents a unique genetic resource for dissecting the complex genetic etiology underlying bone fragility. The purpose of this study was to identify and localize genes associated with bone structure...

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Identifiers

PMID: 26297441
DOI: 10.1016/j.bone.2015.08.013
PMCID: PMC4641024

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Source receipt: pubmed, retrieved 7 Sept 2026.

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