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Article

Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength.

PloS one - 1 Jan 2011

Lagerholm Sofia, Park Hee-Bok, Luthman Holger, Grynpas Marc, McGuigan Fiona, Swanberg Maria, Åkesson Kristina

Abstract excerpt

Susceptibility to osteoporotic fracture is influenced by genetic factors that can be dissected by whole-genome linkage analysis in experimental animal crosses. The aim of this study was to characterize quantitative trait loci (QTLs) for biomechanical and two-dimensional dual-energy X-ray absorptiometry (DXA) phenotypes in reciprocal F2 crosses between diabetic GK and normo-glycemic F344 rat strains and to...

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Share to Absorptiometry, Photon
Share to Biomechanical Phenomena

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Mammalian

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Source

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Identifiers

PMID: 21818327
DOI: 10.1371/journal.pone.0022462
PMCID: PMC3144887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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