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Article

Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2011

Gupta Mayetri, Cheung Ching-Lung, Hsu Yi-Hsiang, Demissie Serkalem, Cupples L Adrienne, Kiel Douglas P, Karasik David

Abstract excerpt

Genome-wide association studies (GWAS) using high-density genotyping platforms offer an unbiased strategy to identify new candidate genes for osteoporosis. It is imperative to be able to clearly distinguish signal from noise by focusing on the best phenotype in a genetic study. We performed GWAS of multiple phenotypes associated with fractures [bone mineral density (BMD), bone quantitative ultrasound (QUS), bone...

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Identifiers

PMID: 21611967
DOI: 10.1002/jbmr.333
PMCID: PMC3312758

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PRKCH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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