Article
Whole-genome scan for linkage to bone strength and structure in inbred Fischer 344 and Lewis rats.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2005
Alam Imranul, Sun Qiwei, Liu Lixiang, Koller Daniel L, Fishburn Tonya, Carr Lucinda G, Econs Michael J, Foroud Tatiana, Turner Charles H
Abstract excerpt
UNLABELLED: A genome-wide genetic linkage analysis identified several chromosomal regions influencing bone strength and structure in F2 progeny of Fischer 344 x Lewis inbred rats. INTRODUCTION: Inbred Fischer 344 (F344) and Lewis (LEW) rats are similar in body size, but the F344 rats have significantly lower BMD and biomechanical strength of the femur and spine compared with LEW rats. The goal of this study was...
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