Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneous Stock Populations for Analysis of Complex Traits.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Woods Leah C Solberg, Mott Richard

Abstract excerpt

Heterogeneous Stock (HS) populations allow for fine-resolution genetic mapping of a variety of complex traits. HS mice and rats were created from breeding together eight inbred strains, followed by maintaining the colony in a manner that minimizes inbreeding. After 50 or more generations of breeding, the resulting animals' chromosomes represent a genetic mosaic of the founders' haplotypes, with the average...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breeding
Share to Chromosome Mapping
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Techniques

Share to Genetics, Population

Share to Models, Statistical

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 27933519
DOI: 10.1007/978-1-4939-6427-7_2
PMCID: PMC5869698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneous Stock Populations for Analysis of Complex Traits.PMID 27933519Read ↗

Genome-wide genetic association of complex traits in heterogeneous stock mice.Semantic proximity Read ↗

QTL mapping in outbred populations: successes and challenges.Semantic proximity Read ↗

QTL fine-mapping with recombinant-inbred heterogeneous stocks and in vitro heterogeneous stocks.Semantic proximity Read ↗

Genetic analysis of complex traits in the emerging Collaborative Cross.Semantic proximity Read ↗

Strategies for mapping and cloning quantitative trait genes in rodents.Semantic proximity Read ↗

Facilitating Complex Trait Analysis via Reduced Complexity Crosses.Semantic proximity Read ↗

High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues.Semantic proximity Read ↗

Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.Semantic proximity Read ↗

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.Semantic proximity Read ↗

Fine-mapping a locus for glucose tolerance using heterogeneous stock rats.Semantic proximity Read ↗

Dissecting quantitative traits in mice.Semantic proximity Read ↗

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.