Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible Association of APOE Genotype with Working Memory in Young Adults.

PloS one - 1 Jan 2015

Sinclair Lindsey I, Button Katherine S, Munafò Marcus R, Day Ian N M, Lewis Glyn

Abstract excerpt

BACKGROUND: Possession of the ε4 allele of the Apolipoprotein E (APOE) gene is associated with an increased risk of Alzheimer's disease. Early adult life effects of ε4 are less well understood. Working memory has been relatively little studied (compared to episodic memory) in relation to APOE genotype despite its importance in cognitive functioning. Our hypothesis was that ε4 would lead to an impairment in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Apolipoproteins E
Share to Cognition

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genotype

Share to Memory, Short-Term

Share to Neuropsychological Tests

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26287823
DOI: 10.1371/journal.pone.0135894
PMCID: PMC4545585

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible Association of APOE Genotype with Working Memory in Young Adults.PMID 26287823Read ↗

Possible positive effect of the APOE ε2 allele on cognition in early to mid-adult life.Semantic proximity Read ↗

Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength.Semantic proximity Read ↗

Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course.Semantic proximity Read ↗

Sex and APOE: A memory advantage in male APOE ε4 carriers in midlife.Semantic proximity Read ↗

Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants.Semantic proximity Read ↗

IQ, Educational Attainment, Memory and Plasma Lipids: Associations with Apolipoprotein E Genotype in 5995 ChildrenSemantic proximity Read ↗

Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study.Semantic proximity Read ↗

The influence of APOE status on episodic and semantic memory: data from a population-based study.Semantic proximity Read ↗

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease.Semantic proximity Read ↗

The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline.Semantic proximity Read ↗

Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults.Semantic proximity Read ↗

The Elusive Nature of APOE ε4 in Mid-adulthood: Understanding the Cognitive ProfileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.