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Article

Clinicopathological characteristics of RHOA mutations in a Central European gastric cancer cohort.

Journal of clinical pathology - 1 Jan 2016

Röcken Christoph, Behrens Hans-Michael, Böger Christine, Krüger Sandra

Abstract excerpt

Genomically stable gastric cancers (GCs) are enriched for the diffuse phenotype and hotspot mutations of RHOA. Here we aimed to validate the occurrence, phenotype and clinicopathological characteristics of RHOA mutant GCs in an independent Central European GC cohort consisting of 415 patients. The RHOA genotype (exon 2 and 3) was correlated with various genotypic, phenotypic and clinicopathological patient...

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Source

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Identifiers

PMID: 26251521
DOI: 10.1136/jclinpath-2015-202980
PMCID: PMC4717431

Genes

RHOA
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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