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Article

RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Apr 2016

Ushiku Tetsuo, Ishikawa Shumpei, Kakiuchi Miwako, Tanaka Atsushi, Katoh Hiroto, Aburatani Hiroyuki, Lauwers Gregory Y, Fukayama Masashi

Abstract excerpt

BACKGROUND: Recent studies have discovered recurrent RHOA mutations in diffuse-type gastric cancers. These reports show mutant RhoA is an important cancer driver and is a potential therapeutic target. This study aims to investigate the clinicopathological features of diffuse-type gastric cancers with RHOA mutation. METHODS: We performed a thorough review of 87 diffuse-type gastric cancers, including 22...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25823974
DOI: 10.1007/s10120-015-0493-0
PMCID: PMC4824805

Genes

RHOA
CLDN18

Provenance

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