Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A distinct role of RhoB in gastric cancer suppression

11 May 2010

Abstract excerpt

Although Rho family GTPases RhoA, RhoB and RhoC share more than 85% amino acid sequence identity, they may play distinct roles in tumor progression. RhoA and RhoC have been suggested to have positive effects on tumor progression, but the role of RhoB in cancer, particularly in gastric cancer, remains unclear. In our study, we have examined the expression levels of these three Rho GTPases in a large panel of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Protein Kinase Regulation and GTPase Signaling
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20473933
DOI: 10.1002/ijc.25445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A distinct role of RhoB in gastric cancer suppressionPMID 20473933Read ↗

Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.Semantic proximity Read ↗

RhoB in cancer suppression.Semantic proximity Read ↗

RhoC is essential for the metastasis of gastric cancerSemantic proximity Read ↗

Rho proteins and cancer.Semantic proximity Read ↗

Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells.Semantic proximity Read ↗

Rho GTPase signaling in the development of colorectal cancerSemantic proximity Read ↗

RHO GTPases in cancer: known facts, open questions, and therapeutic challenges.Semantic proximity Read ↗

RHOJ Induces Epithelial-to-Mesenchymal Transition by IL-6/STAT3 to Promote Invasion and Metastasis in Gastric CancerSemantic proximity Read ↗

Identification of "regulation of RhoA activity panel" as a prognostic and predictive biomarker for gastric cancer.Semantic proximity Read ↗

RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesisSemantic proximity Read ↗

Knockdown of RhoGDI2 represses human gastric cancer cell proliferation, invasion and drug resistance via the Rac1/Pak1/LIMK1 pathwaySemantic proximity Read ↗

Fixing the GAP: The role of RhoGAPs in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.