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Article

Effects of single nucleotide polymorphisms in c-Myc on stable warfarin doses in patients with cardiac valve replacements.

Pharmacogenomics - 1 Jan 2015

Lee Kyung E, Chang Byung C, Park Sunny, Gwak Hye S

Abstract excerpt

AIM: This study aimed to investigate an association between c-Myc SNPs and stable warfarin doses. MATERIALS & METHODS: The influences of genetic polymorphisms on dose requirements were investigated by genotyping ten SNPs in 201 patients with stable warfarin doses; VKORC1 (rs9923231), CYP2C9 (rs1057910), CYP4F2 (rs2108622), GATA4 (rs10090884), c-Myc (rs4645962, , and ) and 8q24...

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Share to Anticoagulants
Share to Cytochrome P-450 Enzyme System
Share to Dose-Response Relationship, Drug
Share to Heart Valves
Share to Polymorphism, Single Nucleotide
Share to Proto-Oncogene Proteins c-myc
Share to Vitamin K Epoxide Reductases
Share to Warfarin

Source

Identifiers

PMID: 26249541
DOI: 10.2217/pgs.15.37

Genes

VKORC1
GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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