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Article

Influence of NR3C1 and VDR polymorphisms on stable warfarin dose in patients with mechanical cardiac valves.

International journal of cardiology - 1 Jun 2017

Lee Kyung Eun, Chung Jee Eun, Yi Boram, Cho Yoon Jeong, Kim Hyun Jeong, Lee Gwan Yung, Kim Joo Hee, Chang Byung Chul, Gwak Hye Sun

Abstract excerpt

OBJECTIVES: The aim of this study was to evaluate the associations between polymorphisms of VKORC1, CYP2C9, CYP4F2, NR3C1 and VDR genes and stable warfarin doses in Korean patients with mechanical heart valves. METHODS: Seventeen single-nucleotide polymorphisms (SNPs) in 204 patients with stable warfarin dose were analyzed: VKORC1 (rs9934438), CYP2C9 (rs1057910), CYP4F2 (rs2108622), NR3C1 (rs41423247, rs1800445,...

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Share to Anticoagulants
Share to Dose-Response Relationship, Drug
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Source

Identifiers

PMID: 28262345
DOI: 10.1016/j.ijcard.2017.02.103

Genes

VDR
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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