Impact of GATA4 variants on stable warfarin doses in patients with prosthetic heart valves.

doi:10.1038/tpj.2014.36

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Article

Impact of GATA4 variants on stable warfarin doses in patients with prosthetic heart valves.

The pharmacogenomics journal - 1 Feb 2015

Jeong E, Lee K E, Jeong H, Chang B C, Gwak H S

Abstract excerpt

Interindividual variability in stable warfarin doses is largely attributed to VKORC1 and CYP2C9 variants. On the basis of a recent finding of the role of GATA4 in control of CYP2C9 expression, we tested a possible effect of GATA4 genotypes on variability in warfarin response using 201 Korean patients with prosthetic cardiac valves. Two single-nucleotide polymorphisms (SNPs), rs2645400 (G>T) and rs4841588 (G>T),...

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Identifiers

PMID: 25026456
DOI: 10.1038/tpj.2014.36

Genes

GATA4
VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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