Article
Influence of UDP-Glucuronosyltransferase Polymorphisms on Stable Warfarin Doses in Patients with Mechanical Cardiac Valves.
Cardiovascular therapeutics - 1 Dec 2015
An Sook Hee, Chang Byung Chul, Lee Kyung Eun, Gwak Hye Sun
Abstract excerpt
AIM: This study aimed to evaluate the effect of uridine diphosphate (UDP)-glucuronosyltransferase (UGT) polymorphisms on warfarin dosing requirements in patients with mechanical cardiac valves. METHODS: A total of 191 patients with stable warfarin doses from the EAST Group of Warfarin were included in this study. The influence of genetic polymorphisms on stable warfarin doses was investigated by genotyping 6...
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