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Article

Clinical and genetic factors associated with warfarin maintenance dose in northern Chinese patients with mechanical heart valve replacement.

Medicine - 1 Jan 2017

Liu Rui, Cao Jian, Zhang Qian, Shi Xin-Miao, Pan Xiao-Dong, Dong Ran

Abstract excerpt

The effects of genetic variants on warfarin dosing vary among different ethnic groups, especially in the Chinese population. The objective of this study was to recruit patients through a rigorous experimental design and to perform a comprehensive screen to identify gene polymorphisms that may influence warfarin dosing in northern Han Chinese patients with mechanical heart valve replacement. Consenting patients...

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Identifiers

PMID: 28079798
DOI: 10.1097/MD.0000000000005658
PMCID: PMC5266160

Genes

VKORC1
APOE
EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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