Article
Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
Gene - 30 Jan 2018
Chung Jee-Eun, Lee Kyung Eun, Chang Byung Chul, Gwak Hye Sun
Abstract excerpt
The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin. Sixteen single nucleotide polymorphisms (SNPs) in 201 patients with stable warfarin doses were analyzed including genes of VKORC1, CYP2C9, CYP4F2, GGCX, EPHX1 and VKORC1L1. Univariate analysis was conducted for the association of genotypes with stable warfarin doses. Multiple...
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