Article
CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2016
Zhang Deng-Feng, Li Jin, Wu Huan, Cui Yue, Bi Rui, Zhou He-Jiang, Wang Hui-Zhen, Zhang Chen, Wang Dong, Kong Qing-Peng, Li Tao, Fang Yiru, Jiang Tianzi, Yao Yong-Gang
Abstract excerpt
The immune response is highly active in Alzheimer's disease (AD). Identification of genetic risk contributed by immune genes to AD may provide essential insight for the prognosis, diagnosis, and treatment of this neurodegenerative disease. In this study, we performed a genetic screening for AD-related top immune genes identified in Europeans in a Chinese cohort, followed by a multiple-stage study focusing on...
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