Article
CR1 in Alzheimer's disease.
Molecular neurobiology - 1 Apr 2015
Zhu Xi-Chen, Yu Jin-Tai, Jiang Teng, Wang Ping, Cao Lei, Tan Lan
Abstract excerpt
The complement component receptor 1 gene (CR1), which encodes a type-I transmembrane glycoprotein, has recently been identified as one of the most important risk genes for late-onset Alzheimer's disease (LOAD). In this article, we reviewed the recent evidence concerning the role of CR1 in LOAD. First, we introduced the structure, localization and physiological function of CR1 in humans. Afterward, we summarized...
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