Article
An Updated Analysis with 85,939 Samples Confirms the Association Between CR1 rs6656401 Polymorphism and Alzheimer's Disease.
Molecular neurobiology - 1 Jan 2015
Shen Ning, Chen Bin, Jiang Yongshuai, Feng Rennan, Liao Mingzhi, Zhang Liangcai, Li Fujun, Ma Guoda, Chen Zugen, Zhao Bin, Li Keshen, Liu Guiyou
Abstract excerpt
The complement receptor 1 (CR1) rs6656401 polymorphism was first identified to be associated with Alzheimer's disease (AD) in European ancestry. However, the following studies reported weak or no significant association in Chinese, Japanese, Korean, African-American, Polish, and Canadian populations. We think that these negative results may have been caused by either relatively small sample sizes compared with...
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