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Article

Immune system-associated genes in patients with Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Oct 2025

Yao Rui, Ouyang Ziyu, Xu Tianyan, Zhu Yuan, Tang Beisha, Li Jinchen, Jiao Bin, Shen Lu, Luo Shilin, Xiao Xuewen

Abstract excerpt

BackgroundAlzheimer's disease (AD) has been linked to the immune system, but the role of immune-related genes in AD remains unclear.ObjectiveTo investigate the association between immune-related genes and AD risk systematically.MethodsWhole-genome sequencing (WGS) was performed on 1516 AD patients and 2010 controls. Genetic analysis of 8260 immune-related genes was conducted using PLINK 1.9 for common variants...

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Source

Identifiers

PMID: 40767049
DOI: 10.1177/13872877251364396

Genes

SAMD9
ABCA7
APOE
HRH1
MAF
GFAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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