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Article

Effect of CR1 Genetic Variants on Cerebrospinal Fluid and Neuroimaging Biomarkers in Healthy, Mild Cognitive Impairment and Alzheimer's Disease Cohorts.

Molecular neurobiology - 1 Jan 2017

Zhu Xi-Chen, Wang Hui-Fu, Jiang Teng, Lu Huan, Tan Meng-Shan, Tan Chen-Chen, Tan Lin, Tan Lan, Yu Jin-Tai

Abstract excerpt

The complement component (3b/4b) receptor 1 gene (CR1) is considered as one of the most important genetic susceptibility loci in Alzheimer's disease (AD). However, to date, few studies were performed to discover the possible effect of CR1 genetic variants on AD pathology in the brain. Here, we evaluated the potential role of CR1 common variants in AD-related pathology by assessing neuroimaging biomarkers and...

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PMID: 26742530
DOI: 10.1007/s12035-015-9638-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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