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Article

Complement gene single nucleotide polymorphisms and biomarker endophenotypes of Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Daborg Jonny, Holmgren Sandra, Abramsson Alexandra, Andreasson Ulf, Zetterberg Madeleine, Nilsson Staffan, Minthon Lennart, Skoog Ingmar, Blennow Kaj, Pekna Marcela, Hanse Eric, Zetterberg Henrik

Abstract excerpt

The complement system has been implicated in both physiological synapse elimination and Alzheimer's disease (AD). Here, we investigated associations between four single nucleotide polymorphisms (SNPs) in complement genes and cerebrospinal fluid (CSF) biomarkers for AD in 452 neurochemically or neuropathologically verified AD cases and 678 cognitively normal controls. None of the SNPs associated with risk of AD...

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PMID: 23313922
DOI: 10.3233/JAD-121930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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