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Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells

6 Nov 2024

Abstract excerpt

BACKGROUND: The placenta is essential for nutrient exchange and hormone production between the mother and the developing fetus and serves as an invaluable model for epigenetic research. Most epigenetic studies of the human placenta have used whole placentas from term pregnancies and have identified the presence of partially methylated domains (PMDs). However, the origin of these domains, which are typically...

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PMID: 39506688
DOI: 10.1186/s12864-024-10986-9

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