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Article

A complex association between DNA methylation and gene expression in human placenta at first and third trimesters

13 Jul 2017

Abstract excerpt

The human placenta is a maternal-fetal organ essential for normal fetal development and maternal health. During pregnancy, the placenta undergoes many structural and functional changes in response to fetal needs and environmental exposures. Previous studies have demonstrated widespread epigenetic and gene expression changes from early to late pregnancy. However, on the global level, how DNA methylation changes...

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PMID: 28704530
DOI: 10.1371/journal.pone.0181155

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