Article

DNA methylation reprogramming in marsupial embryos is restricted to the extraembryonic lineage

2025-12-22

Abstract excerpt

<title>Abstract</title> <p>DNA methylation (5mC) is an epigenetic mark that plays a critical role in defining cell fate. Following fertilisation, DNA methylation inherited from gametes must be reprogrammed to establish totipotency and enable the parental-to-zygotic transition. To accomplish this, non-mammalian vertebrates such as zebrafish and medaka subtly reprogram maternal 5mC profiles while maintaining high m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 01c912df-f2c7-577e-a790-85daf3d4d268
DOI: 10.21203/rs.3.rs-8110586/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA methylation reprogramming in marsupial embryos is restricted to the extraembryonic lineageDOI 10.21203/rs.3.rs-8110586/v1Read

DNA methylation reprogramming in marsupial embryos is restricted to the extraembryonic lineageSemantic proximity Read

Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian PlacentasSemantic proximity Read

Extensive DNA methylome rearrangement during early lamprey embryogenesisSemantic proximity Read

Epigenetic dynamics during preimplantation developmentSemantic proximity Read

DNA methylation and DNA methyltransferases.Semantic proximity Read

Distinct Patterns of Gene-Specific Methylation in Mammalian Placentas: Implications for Placental Evolution and FunctionSemantic proximity Read

Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryoSemantic proximity Read

Molecular evolution of <i>DNMT1</i> in vertebrates: duplications in marsupials followed by positive selectionSemantic proximity Read

Spatiotemporal DNA Methylome Dynamics of the Developing Mammalian FetusSemantic proximity Read

Developmental Genome-Wide DNA Methylation Asymmetry Between Mouse Placenta and EmbryoSemantic proximity Read

Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropodsSemantic proximity Read

Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprintingSemantic proximity Read