Article
Regulatory Rewiring in a Cross Causes Extensive Genetic Heterogeneity.
Genetics - 1 Oct 2015
Matsui Takeshi, Linder Robert, Phan Joann, Seidl Fabian, Ehrenreich Ian M
Abstract excerpt
Genetic heterogeneity occurs when individuals express similar phenotypes as a result of different underlying mechanisms. Although such heterogeneity is known to be a potential source of unexplained heritability in genetic mapping studies, its prevalence and molecular basis are not fully understood. Here we show that substantial genetic heterogeneity underlies a model phenotype--the ability to grow invasively--in...
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