Pooled segregant sequencing reveals genetic determinants of yeast pseudohyphal growth.

Abstract excerpt

The pseudohyphal growth response is a dramatic morphological transition and presumed foraging mechanism wherein yeast cells form invasive and surface-spread multicellular filaments. Pseudohyphal growth has been studied extensively as a model of conserved signaling pathways controlling stress responses, cell morphogenesis, and fungal virulence in pathogenic fungi. The genetic contribution to pseudohyphal growth is...

Topics

• Alleles
• Cell Polarity
• Cytoskeletal Proteins
• Gene Expression Regulation, Fungal
• Genetic Linkage
• Hyphae
• Microfilament Proteins
• Mitochondrial Membranes
• Mitochondrial Proteins
• Mitogen-Activated Protein Kinase Kinases
• Mitogen-Activated Protein Kinases
• Mutation
• Phenotype
• Saccharomyces cerevisiae