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Article

Cell-to-cell stochastic variation in gene expression is a complex genetic trait.

PLoS genetics - 11 Apr 2008

Ansel Juliet, Bottin Hélène, Rodriguez-Beltran Camilo, Damon Christelle, Nagarajan Muniyandi, Fehrmann Steffen, François Jean, Yvert Gaël

Abstract excerpt

The genetic control of common traits is rarely deterministic, with many genes contributing only to the chance of developing a given phenotype. This incomplete penetrance is poorly understood and is usually attributed to interactions between genes or interactions between genes and environmental conditions. Because many traits such as cancer can emerge from rare events happening in one or very few cells, we...

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Identifiers

PMID: 18404214
DOI: 10.1371/journal.pgen.1000049
PMCID: PMC2289839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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