Article
The Hidden Complexity of Mendelian Traits across Natural Yeast Populations.
Cell reports - 26 Jul 2016
Hou Jing, Sigwalt Anastasie, Fournier Téo, Pflieger David, Peter Jackson, de Montigny Jacky, Dunham Maitreya J, Schacherer Joseph
Abstract excerpt
Mendelian traits are considered to be at the lower end of the complexity spectrum of heritable phenotypes. However, more than a century after the rediscovery of Mendel's law, the global landscape of monogenic variants, as well as their effects and inheritance patterns within natural populations, is still not well understood. Using the yeast Saccharomyces cerevisiae, we performed a species-wide survey of Mendelian...
Topics
- Genetic Variation
- Phenotype
- Quantitative Trait Loci
- Saccharomyces cerevisiae