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Article

Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions.

PLoS genetics - 1 Oct 2015

Taylor Matthew B, Ehrenreich Ian M

Abstract excerpt

Disruption of certain genes can reveal cryptic genetic variants that do not typically show phenotypic effects. Because this phenomenon, which is referred to as 'phenotypic capacitance', is a potential source of trait variation and disease risk, it is important to understand how it arises at the genetic and molecular levels. Here, we use a cryptic colony morphology trait that segregates in a yeast cross to explore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26484664
DOI: 10.1371/journal.pgen.1005606
PMCID: PMC4618523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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