Article
Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae.
PLoS genetics - 1 Jan 2015
Treusch Sebastian, Albert Frank W, Bloom Joshua S, Kotenko Iulia E, Kruglyak Leonid
Abstract excerpt
Signaling pathways enable cells to sense and respond to their environment. Many cellular signaling strategies are conserved from fungi to humans, yet their activity and phenotypic consequences can vary extensively among individuals within a species. A systematic assessment of the impact of naturally occurring genetic variation on signaling pathways remains to be conducted. In S. cerevisiae, both response and...
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