Article

Multiple layers of cryptic genetic variation underlie a yeast complex trait

2018-11-07

Abstract excerpt

Cryptic genetic variation may be an important contributor to heritable traits, but its extent and regulation are not fully understood. Here, we investigate the cryptic genetic variation underlying a Saccharomyces cerevisiae colony phenotype that is typically suppressed in a cross of the lab strain BY4716 (BY) and a derivative of the clinical isolate 322134S (3S). To do this, we comprehensively map the trait's gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7904ce64-835d-5a55-8eb9-813d41f3b10a
DOI: 10.1101/465278

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiple layers of cryptic genetic variation underlie a yeast complex traitDOI 10.1101/465278Read

Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions.Semantic proximity Read

Diverse genetic architectures lead to the same cryptic phenotype in a yeast cross.Semantic proximity Read

The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae.Semantic proximity Read

Genetic dissection of complex traits in yeast: insights from studies of gene expression and other phenotypes in the BYxRM cross.Semantic proximity Read

Dynamic genetic architecture of yeast response to environmental perturbation shed light on origin of cryptic genetic variation.Semantic proximity Read

Regulatory Rewiring in a Cross Causes Extensive Genetic Heterogeneity.Semantic proximity Read

Unraveling the Genetic Architecture of Cryptic Genetic VariationSemantic proximity Read

Differential Regulation of Cryptic Genetic Variation Shapes the Genetic Interactome Underlying Complex Traits.Semantic proximity Read

Genome-scale analysis of interactions between genetic perturbations and natural variation.Semantic proximity Read

Uncovering cryptic genetic variation.Semantic proximity Read

Gene-gene and gene-environment interactions in complex traits in yeast.Semantic proximity Read

Genotype to phenotype: a complex problem.Semantic proximity Read