Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor.

Journal of biochemistry - 1 Jan 2016

Choudhary Pooja, Loewen Michele C

Abstract excerpt

Although well documented for mammalian G-protein-coupled receptors, alternate functionalities and associated alternate signalling remain to be unequivocally established for the Saccharomyces cerevisiae pheromone Ste2p receptor. Here, evidence supporting alternate functionalities for Ste2p is re-evaluated, extended and quantified. In particular, strong mating and constitutive signalling mutations, focusing on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Checkpoints
Share to Mutagenesis, Site-Directed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Transport

Share to Receptors, Mating Factor

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 26232403
DOI: 10.1093/jb/mvv072
PMCID: PMC4882639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor.PMID 26232403Read ↗

The directed evolution of ligand specificity in a GPCR and the unequal contributions of efficacy and affinity.Semantic proximity Read ↗

Strategies for isolating constitutively active and dominant-negative pheromone receptor mutants in yeast.Semantic proximity Read ↗

Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions.Semantic proximity Read ↗

Distinguishing Critical, Beneficial, Neutral and Harmful Mutations Uncovered in the Directed Evolution of a Yeast Membrane ReceptorSemantic proximity Read ↗

The Leu-132 of the Ste4(Gbeta) subunit is essential for proper coupling of the G protein with the Ste2 alpha factor receptor during the mating pheromone response in yeast.Semantic proximity Read ↗

Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.Semantic proximity Read ↗

Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant.Semantic proximity Read ↗

Engineered cell differentiation and sexual reproduction in probiotic and mating yeastsSemantic proximity Read ↗

A role for a complex between activated G protein-coupled receptors in yeast cellular mating.Semantic proximity Read ↗

Interaction between transmembrane domains five and six of the alpha -factor receptor.Semantic proximity Read ↗

The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors.Semantic proximity Read ↗

The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.