Article
A role for a complex between activated G protein-coupled receptors in yeast cellular mating.
Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2007
Shi Chunhua, Kaminskyj Susan, Caldwell Sarah, Loewen Michèle C
Abstract excerpt
Cell-cell fusion is a fundamental process that facilitates a wide variety of biological events in organisms ranging from yeast to humans. However, relatively little is actually understood with respect to fusion mechanisms. In the model organism Saccharomyces cerevisiae, mating of opposite-type cells is triggered by pheromone activation of the G protein-coupled receptors, alpha-factor receptor (Ste2p) and a-factor...
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