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Article

Association of Stress-Related Genetic Polymorphisms and Stressful Life Events With Alcohol Use Disorder in a Brazilian Population.

Stress and health : journal of the International Society for the Investigation of Stress - 1 Aug 2026

Céspedes Isabel Cristina, Conte Rafael, Ota Vanessa Kiyomi, Mazzotti Diego Robles, Wscieklica Tatiana, Galduróz José Carlos Fernandes, Varela Patrícia, Pesquero João Bosco, Pereira-Rufino Laís da Silva, Souza-Formigoni Maria Lucia Oliveira

Abstract excerpt

Alcohol Use Disorder (AUD) is a multifactorial condition shaped by genetic predispositions and neurophysiological, behavioural, and environmental factors. Chronic stress and trauma are key drivers of harmful alcohol use. This study aimed to investigate, in a Brazilian admixed population, the associations and interactions between genetic variants related to the CRFergic, noradrenergic, and glucocorticoid receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Corticotropin-Releasing Hormone

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Source

Identifiers

PMID: 42375127
DOI: 10.1002/smi.70193

Genes

CRHR2
IDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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