Article
Mineralocorticoid receptor genotype moderates the association between physical neglect and serum BDNF.
Journal of psychiatric research - 1 Dec 2014
Bortoluzzi Andressa, Salum Giovanni Abrahão, Blaya Carolina, Silveira Patrícia Pelufo, Grassi-Oliveira Rodrigo, da Rosa Eduarda Dias, de Aguiar Bianca Wollenhaupt, Stertz Laura, Bosa Vera Lúcia, Schuch Ilaine, Goldani Marcelo, Kapczinski Flavio, Leistner-Segal Sandra, Manfro Gisele Gus
Abstract excerpt
The objective of this study is to investigate if a polymorphism in the NR3C2 gene moderates the association between childhood trauma on serum levels of brain derived neurothrophic factor (sBDNF). sBDNF was used here as a general marker of alteration in brain function. This is a community cross sectional study comprising 90 adolescents (54 with anxiety disorders). DNA was extracted from saliva in order to genotype...
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