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Article

Epileptogenesis and epileptic maturation in phosphorylation site-specific SNAP-25 mutant mice.

Epilepsy research - 1 Sept 2015

Watanabe Shigeru, Yamamori Saori, Otsuka Shintaro, Saito Masanori, Suzuki Eiji, Kataoka Masakazu, Miyaoka Hitoshi, Takahashi Masami

Abstract excerpt

Snap25(S187A/S187A) mouse is a knock-in mouse with a single amino acid substitution at a protein kinase C-dependent phosphorylation site of the synaptosomal-associated protein of 25 kDa (SNAP-25), which is a target-soluble NSF attachment protein receptor (t-SNARE) protein essential for neurotransmitter release. Snap25(S187A/S187A) mice exhibit several distinct phenotypes, including reductions in dopamine and...

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Source

Identifiers

PMID: 26220374
DOI: 10.1016/j.eplepsyres.2015.05.004

Genes

NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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