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Article

Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease.

PloS one - 1 Jan 2015

Zhu Zuobin, Yuan Dejian, Luo Denghui, Lu Xitong, Huang Shi

Abstract excerpt

Parkinson disease (PD) is the second most common neurodegenerative disorder in the aged population and thought to involve many genetic loci. While a number of individual single nucleotide polymorphisms (SNPs) have been linked with PD, many remain to be found and no known markers or combinations of them have a useful predictive value for sporadic PD cases. The collective effects of genome wide minor alleles of...

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PMID: 26207627
DOI: 10.1371/journal.pone.0133421
PMCID: PMC4514478

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