Article

Genome-wide assessment identifies novel runs of homozygosity linked to Parkinson’s disease etiology across diverse ancestral populations

2025-05-22

Abstract excerpt

<h4>Objective</h4> We conducted the first large-scale, multi-ancestral investigation of Parkinson’s disease (PD) to examine the impact of genome-wide homozygosity on disease risk and age at onset. Using genotyping, imputed, and whole-genome sequencing (WGS) data from 16,599 PD cases and 13,585 controls across nine ancestral populations from the Global Parkinson’s Genetics Program, we aimed to identify novel region...

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Literature Corpus work: acdf6059-34b3-5e75-abe3-9b9529fc9bc8
DOI: 10.1101/2025.05.21.25328076

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