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Article

The relationship between the minor allele content and Alzheimer's disease.

Genomics - 1 May 2020

Chen Hongyao, Lei Xiaoyun, Yuan Dejian, Huang Shi

Abstract excerpt

Alzheimer's disease (AD) is a chronic neurodegenerative disease. The genetic risk factors of AD remain better understood. Using previously published dataset of common single nucleotide polymorphisms (SNPs), we studied the association between the minor allele content (MAC) in an individual and AD. We found that AD patients have higher average MAC values than matched controls. We identified a risk prediction model...

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PMID: 31982476
DOI: 10.1016/j.ygeno.2020.01.015

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